Lecturer of Medical Microbiology and Immunology Department, Faculty of Medicine, Zagazig University, Egypt
Abstract
Background: Helicobacter pylori may be associated with unexplained iron-deficiency anemia (IDA). Hepcidin is an acute-phase reactant but its relation to H. pylori and IDA has not been elucidated. Objective: to investigate serum hepcidin in H. pylori infected patients and its role in IDA. Methodology: This study was performed on 70 patients infected by Helicobacter pylori. They were divided into two groups, group A: 35 H. pylori infected patients without iron deficiency anemia and group B: 35 H. pylori infected patients with iron deficiency anemia. Serum hepcidin was measured by ELISA in both groups while iron, ferritin and total iron binding capacity were estimated in group B. Results: Serum hepcidin was significantly higher in patients with H. pylori infection and iron deficiency anemia. However, non-significant correlation between hepcidin and both iron and ferritin were found. Conclusion: Helicobacter pylori could modulate serum hepcidin level in patients with iron deficiency anemia.
Morad, E. (2021). Relationship between Hepcidin and Iron Deficiency Anemia in Helicobacter pylori Infected Patients. Egyptian Journal of Medical Microbiology, 30(3), 21-27.
MLA
Emad Morad. "Relationship between Hepcidin and Iron Deficiency Anemia in Helicobacter pylori Infected Patients". Egyptian Journal of Medical Microbiology, 30, 3, 2021, 21-27.
HARVARD
Morad, E. (2021). 'Relationship between Hepcidin and Iron Deficiency Anemia in Helicobacter pylori Infected Patients', Egyptian Journal of Medical Microbiology, 30(3), pp. 21-27.
VANCOUVER
Morad, E. Relationship between Hepcidin and Iron Deficiency Anemia in Helicobacter pylori Infected Patients. Egyptian Journal of Medical Microbiology, 2021; 30(3): 21-27.
)
View on SCiNiTO