Role of Oral Corticosteroids in Treatment of Home Isolated COVID-19 Patients

Document Type : New and original researches in the field of Microbiology.

Authors

1 Lecturer of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

2 Resident of Gastroenterology, Ahmed Maher Teaching Hospital, Cairo, Egypt

3 Assistant Professor of Pulmonary Medicine, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

4 Assistant Professor of Internal Medicine, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Abstract

Background: There is a debate over the efficacy of corticosteroids (CS) in management of Coronavirus diseases 2019 (COVID-19); yet, few are declared about its role in treatment of mild conditions. Objectives: in this study, we aimed at investigating the role of corticosteroids in mild cases of COVID-19. Methodology: in a case control study, we included 100 patients with mild COVID-19. The incidence of improvement, disappearance of symptoms, appearance of new symptoms and deterioration were compared between cases and control group. Results: More than three fourths of the study participants showed improvement of symptoms, with disappearance of symptoms in 64% and 85% of group 1 and group 2, respectively. Only few numbers of patients deteriorated. Noticeably, a remarkable number of patients expressed new symptoms by the end of the study. Conclusions: corticosteroids has no role in clinical progression of cases with mild COVID-19. CS use should be reserved for severe symptoms of COVID-19.

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