Hemodialysis Catheter-Related Infections among Pediatric Patients in Mansoura University Children Hospital

Document Type : New and original researches in the field of Microbiology.

Authors

1 Department of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University, Mansoura, Egypt

2 Department of Pediatrics, Faculty of medicine, Mansoura University, Mansoura, Egypt

3 Department of Medical Microbiology and Immunology

Abstract

Background: Infection is the second leading cause of death in patients on hemodialysis (HD) after cardiovascular disease. Using a central venous catheter (CVC) is the most important risk factor for blood stream infection in HD patients, which can lead to life-threatening complications. Central venous catheter related infections (CVC-RI) may be local access site infection (LASI) or access related blood stream infection (ARBSI). Objectives: We performed a descriptive longitudinal (prospective) study to detect incidence of hemodialysis CVC-RI in Mansoura University Children Hospital (MUCH), determine risk factors and provide appropriate infection control interventions. Methodology: A total of 114 hemodialysis catheters were collected from 100 patients with CVC inserted more than 48 hours. Results: From the 114 collected, 27 (23.7%) CVC-RI were documented with incidence of 8.6 per 1000 CVC-days. Among these CVC-RI, 24 were LASI (21.1%, 7.7 per 1000 CVC-days) and 3 were ARBSI (2.6%, 0.9 per 1000 CVC-days). The commonest micro-organism detected causing CVC-RI was staphylococcus aureus. Conclusions: Femoral catheters, associated co-morbidities as D.M and immunosuppression and low compliance to preventive measures of infection during maintenance of the catheters were significant risk factors for CVC-RIs. 

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