Antimicrobial Susceptibility Patterns of Nosocomial Pseudomonas aeruginosa Strains Isolated from Clinical Specimens in Tanta University Hospitals

Document Type : New and original researches in the field of Microbiology.

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Department of Medical Microbiology and Immunology, Faculty of Medicine, Tanta University, Egypt

Abstract

Background: Pseudomonas aeruginosa is an ubiquitous microbe capable of infecting practically any tissues. Pulmonary tract, skin and blood stream infections with multi-drug resistant (MDR) P. aeruginosa represent major causes of morbidity and mortality especially in immunocompromised patients e.g., patients with cystic fibrosis. Objective: To detect the susceptibility pattern of nosocomial P. aeruginosa isolates collected from different clinical specimens in Tanta University Hospitals. Methodology: Thirty isolates of P. aeruginosa were collected (10 from respiratory tract infection samples, 10 from burn samples and 10 from blood stream infections). Samples were introduced to macroscopic, microscopic, bacteriological examination and susceptibility testing using disc diffusion method. Results: There wasno significant difference detected between isolates of P. aeruginosa in relation to gender or age, while there was a significant antibiotic resistance against the used antibiotics in blood specimens more than respiratory and burn specimens. Conclusion: Significant detection of MDR P. aeruginosa isolates ensures the importance of controlling antibiotic misuse and self-prescriptions.

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