Genotyping of Human papilloma virus from warts in Egyptian patients

Document Type : New and original researches in the field of Microbiology.

Authors

1 Medical Microbiology and Immunology Department, Faculty of Medicine, Zagazig University

2 Dermatology, Venereology and Andrology Department at Zagazig University Hospitals

Abstract

Background: Warts are common viral infections of the skin that are caused by human papillomavirus (HPV). There are more than 200 HPV genotypes up till now. Objective: To identify HPV genotype distribution among wart patients. Methodology: A cross sectional study was conducted on 78 patients with warts. Shave biopsy was taken from wart cases for detection of HPV by conventional PCR. HPV genotyping was performed using real time PCR. Results: HPV DNA was detected in 50 (64.1%) of all biopsy samples while 28 (35.9%) of samples were negative. The most frequently detected genotype was HPV-52 (7.1 %) from HPV positive samples. Conclusion: obtaining results can increase the knowledge regarding the prevalence of HPV and its type distribution in Egypt. This may contribute to create a national prevention program for HPV.

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