The Effect of Eradication Treatment of Helicobacter Pylori on The Clinical Outcome of Patients with Pityriasis Versicolor

Document Type : New and original researches in the field of Microbiology.

Authors

1 Department of Dermatology, Andrology & STDs, Faculty of Medicine, Mansoura University, Egypt

2 Department of Public Health and Community Medicine, Faculty of Medicine, Mansoura University, Egypt

3 Medical Microbiology and Immunology Department, Faculty of medicine, Mansoura University, Egypt

Abstract

Background: Although Pityriasis Versicolor (PVC) occurs in healthy individuals, numerous factors predispose to PVC. Helicobacter Pylori (HP) was found to be. related to some dermatological disorders as vitiligo, atopic dermatitis, chronic spontaneous urticaria, and lichen planus. Objective: To evaluate the frequency of HP in. patients. with PVC and the effectiveness of HP eradication treatment on the clinical outcome of PVC. Methodology: A cross-sectional study. was conducted on two hundred and sixteen patients who were subjected to history taking, dermatological examination, Wood’s lamp, direct. microscopic examination of skin scraping with KOH 10%, and HP stool Ag test. Fifty-seven patients with PVC were positive for HP by stool Ag test and were randomly divided into 3 equal groups (n=19), group A included patients treated for PVC only, group B included patients treated for HP only, and Group C included patients treated for both PVC & HP. Follow-up was done after 1 month for all groups clinically and by Wood's lamp to detect clearance of lesions. Results: HP stool Ag test was positive in about one-quarter (26.4%) of PVC patients. Complete disappearance of PVC was recorded in the majority of cases in Group A (89.5%), compared to 52.6% of those in Group C. while in Group B, none of the cases improved clinically. Conclusion: About one-quarter of PVC patients were positive for HP. The use of HP eradication treatment alone did not affect PVC improvement, while there was significant improvement in PVC with both combined treatment and the treatment of PV alone groups.

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