Assessment of Antibiotic Sensitivity of Pseudomonas aeruginosa Isolated from Different Clinical Samples

Document Type : New and original researches in the field of Microbiology.

Authors

1 University of Kufa, College of Science / Department of Pathological Analyses, Iraq

2 Department of Medical Laboratory Technologies, College of health and medical techniques Kufa, Furat AL-Awast Technical University

Abstract

Background: One of the most significant threats to global public health and development is antimicrobial resistance (AMR). Pseudomonas aeruginosa (P. aeruginosa) is directly associated with the issue of AMR and is a major cause of both chronic lifelong diseases and life-threatening acute infections. In Iraq, the rising prevalence of carbapenem-resistant P. aeruginosa poses a substantial threat to public health. Objectives: This study aimed to compare and evaluate the results of drug sensitivity testing for P. aeruginosa isolates from different clinical samples. Methodology: Different samples were collected from clinical cases attending Al-Sadder Medical City Hospital, Iraq these were wounds, otitis media, urinary tract infections (UTIs) and vaginitis. P. aeruginosa was isolated and identification by the routine bacteriological methods and validated by using the VITEK® 2 system. The antibiotic sensitivity of the isolates was determined by AST techniques. Result: One hundred P. aeruginosa strains were identified. The results indicated that the majority of P. aeruginosa showed high resistance to Amoxicillin + Clavulanic acid (AMC), In contrast, there was significantly less resistance to (IPM) Imipenem. Conclusion: Imipenem (IPM) and (MEM) Meropenem were the promising antimicrobial agents used to treat the P. aeruginosa infections.

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